You can disable the keyboard shortcuts, the so-called sticky keys, through a group policy. This is a user setting, and although there's no true policy for this, you can disable it through a group policy preference registry entry:

HKEY_CURRENT_USER\Control Panel\Accessibility\StickyKeys\Flags="506"

Navigate to:

User Configuration → Preferences → Windows Settings → Registry

There, create a new entry:

• Action: Update
• Hive: HKEY_CURRENT_USER
• Key path: Control Panel\Accessibility\StickyKeys
• Value name: Flags
• Value type: REG_SZ
• Value data: 506