When migrating from McAfee to another antivirus, you need to uninstall McAfee Enterprise. When you have not installed it using GPO, it may become quite the task if you have a lot of clients to uninstall the product from. If you have a Windows Domain (optionally using GPO), you can do the uninstall via a logon script.

The installation can be performed by manually uninstalling the product using msiexec. This initiates a proper uninstallation procedure, and will result in a silent uninstall of McAfee Enterprise. Depending on the version you're using, adjust the GUID you see here:

VirusScan Enterprise 8.8:
msiexec /x {CE15D1B6-19B6-4D4D-8F43-CF5D2C3356FF} REMOVE=ALL REBOOT=R /q



VirusScan En  ...