When migrating from McAfee to another antivirus, you need to uninstall McAfee Enterprise. When you have not installed it using GPO, it may become quite the task if you have a lot of clients to uninstall the product from. If you have a Windows Domain (optionally using GPO), you can do the uninstall via a logon script.

The installation can be performed by manually uninstalling the product using msiexec. This initiates a proper uninstallation procedure, and will result in a silent uninstall of McAfee Enterprise. Depending on the version you're using, adjust the GUID you see here:

• VirusScan Enterprise 8.8:
  

  msiexec /x {CE15D1B6-19B6-4D4D-8F43-CF5D2C3356FF} REMOVE=ALL REBOOT=R /q

• VirusScan Enterprise 8.7i:
  

  msiexec /x {147BCE03-C0F1-4C9F-8157-6A89B6D2D973} REMOVE=ALL REBOOT=R /q

• VirusScan Enterprise 8.5i:
  

  msiexec.exe /x {35C03C04-3F1F-42C2-A989-A757EE691F65} REMOVE=ALL REBOOT=R /q

• VirusScan Enterprise 8.0i:
  

  msiexec.exe /x {5DF3D1BB-894E-4DCD-8275-159AC9829B43} REMOVE=ALL REBOOT=R /q

Putting this in a GPO (through script) or a logon script will easily uninstall the product on your clients.