When attempting to send and receive e-mail in Outlook 2010, you may get the error:

Error

Outlook data file cannot be accessed (0x8004010F)

This occurs when the Outlook profile is somehow corrupted.

You can attempt to resolve the issue by re-setting the delivery location in your Accounts, but sometimes this does not work, and the delivery location remains unset. In this case, you have to create a new Outlook profile, recreate your e-mail accounts in it, set the delivery location and reopen any other Outlook data files.