I came across this application when I was looking into software that does just that:
It enables synchronization of Outlook/Exchange folders with a relational database; anything with an ODBC driver is supported (MS-SQL, MySQL, ...).
Found this article, showing you how to lock down Firefox.
This is quite useful when deploying Firefox on, for instance, a Terminal Server.
If you're looking for a better defrag, check out UltraDefrag:
Some highlights of the software (as told on their site):